According to the Mayo Clinic study, the average person burned 100 extra calories every hour while walking slowly at 1 mile per hour rather than sitting in a chair.
Dr. Levine of the Mayo Clinic believes that if individuals were to replace 8 hours a day of sitting at their "normal" desk with a Treadmill Desk, and if other components of energy balance were constant, a weight loss of 57 pounds a year could occur.
Research being conducted by James Levine, M.D. at the Mayo Clinic in Rochester has begun to reveal the many benefits of walking and standing throughout the day instead of sitting. His work has shown that standing and walking can increase daily calorie expenditure in a way that will contribute to improved measures of health and weight. Just standing in place will cause you to burn 20 calories per hour more than sitting. Some offices are being equipped with special walkstations so workers who spend hours in front of a computer can walk slowly (as slow as 1 MPH will do it) while continuing to walk as they would if they were sitting at a traditional workstation. These offices are also working to facilitate the holding of meetings while walking instead of sitting. For a person walking at the leisurely pace of 1 MPH that translates into 100 to 130 calories/hour more than sitting and for an 8 hour day this potentially could lead to losing 40 pounds per year.
I have been experimenting with this standing approach to daily living during the business day. I have found that it contributes to my 18,333 daily step goal. As I stand I tend to move about and surely add to my step count. My personal experience has shown that this number of steps and now adding 20 calories per hour more by standing instead of sitting is helping me to maintain my healthy weight by burning all of the calories I consume each day. Given that I am now at a healthy weight my primary goal is to remain in what is referred to as a net zero state of calorie balance so that I just maintain the 45 pounds I have lost over the years.
Now get the Treadmill Desk - Signature 9000 for an affordable price. The research is real, the results are real, and yes, the price of the new Signature Treadmill Desk is only $1995.

Fit Fact: Why sitting makes you fat
http://exercise.about.com/b/2008/09/12/fit-fact-why-sitting-makes-you-fat.htm#gB3
Friday September 12, 2008
You might want to stand up while you read this, especially when you find out what some scientists have discovered about sitting.
We all know that sitting can contribute to weight problems and common sense tells us that's because sitting doesn't burn as many calories as, say, standing or walking. But, that isn't the only issue with sitting.
In a study published in Diabetes, scientists found that when we sit for long periods of time, the enzymes responsible for burning fat actually shut down. Not only that, but sitting too much can also lower HDL ('good' cholesterol) and lead to a slower metabolism. Even if you exercise later in the day, that won't necessarily undo the damage done by sitting.
The question these scientists are asking, and maybe the question some of us are wondering is: "Can the average adult who already does not follow the public health policy prescribing regular moderate-vigorous exercise become even more unhealthy in the coming years if they sit too much and do not maintain sufficient daily nonexercise physical activity?"
The answer to that is probably a yes, unless we do something about it. The good news is that just standing up can kick your fat-burning enzymes into gear.
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